全文获取类型
收费全文 | 35967篇 |
免费 | 1926篇 |
国内免费 | 648篇 |
专业分类
耳鼻咽喉 | 559篇 |
儿科学 | 751篇 |
妇产科学 | 4927篇 |
基础医学 | 1409篇 |
口腔科学 | 574篇 |
临床医学 | 3477篇 |
内科学 | 4833篇 |
皮肤病学 | 352篇 |
神经病学 | 1110篇 |
特种医学 | 689篇 |
外国民族医学 | 2篇 |
外科学 | 8172篇 |
综合类 | 4168篇 |
现状与发展 | 2篇 |
预防医学 | 3149篇 |
眼科学 | 755篇 |
药学 | 2104篇 |
102篇 | |
中国医学 | 508篇 |
肿瘤学 | 898篇 |
出版年
2024年 | 71篇 |
2023年 | 673篇 |
2022年 | 1252篇 |
2021年 | 1727篇 |
2020年 | 1678篇 |
2019年 | 1387篇 |
2018年 | 1304篇 |
2017年 | 1284篇 |
2016年 | 1307篇 |
2015年 | 1227篇 |
2014年 | 2528篇 |
2013年 | 2583篇 |
2012年 | 1865篇 |
2011年 | 2101篇 |
2010年 | 1731篇 |
2009年 | 1770篇 |
2008年 | 1681篇 |
2007年 | 1622篇 |
2006年 | 1533篇 |
2005年 | 1304篇 |
2004年 | 1152篇 |
2003年 | 988篇 |
2002年 | 742篇 |
2001年 | 660篇 |
2000年 | 533篇 |
1999年 | 405篇 |
1998年 | 390篇 |
1997年 | 358篇 |
1996年 | 283篇 |
1995年 | 236篇 |
1994年 | 246篇 |
1993年 | 218篇 |
1992年 | 203篇 |
1991年 | 171篇 |
1990年 | 132篇 |
1989年 | 127篇 |
1988年 | 133篇 |
1987年 | 104篇 |
1986年 | 69篇 |
1985年 | 137篇 |
1984年 | 112篇 |
1983年 | 67篇 |
1982年 | 91篇 |
1981年 | 76篇 |
1980年 | 58篇 |
1979年 | 50篇 |
1978年 | 47篇 |
1977年 | 37篇 |
1976年 | 20篇 |
1975年 | 28篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
Frank Makowiec Stefan Post Hans-Detlev Saeger Norbert Senninger Heinz Becker Michael Betzler Heinz J. Buhr Ulrich T. Hopt German Advanced Surgical Treatment Study Group 《Journal of gastrointestinal surgery》2005,9(8):1080-1087
Despite decreasing mortality rates, morbidity is still high after pancreatic head resection. Comparative data in the United
States and Europe show a relationship between hospital volume and mortality. Treatment strategies vary frequently, partially
because of the lack of evidence-based data. We performed a multi-institutional analysis in Germany evaluating current numbers,
indications, techniques, and complication rates of pancreatic head resection. Questionnaires were completed by seven high-volume
surgical departments regarding quantitative and qualitative aspects of pancreatic head resections in the period from 1999
to 2004 (five prospective and two retrospective institutional databases). A total of 1454 pancreatic head resections (944
for malignancy) were reported. Mean annual hospital volume ranged from 14 to 52 (10 to 43 in malignancy). Mortality was between
1.1% and 4.8%, morbidity was between 24% and 46%, and pancreatic leakage was between 9% and 20%. In malignant disease, all
centers perform standard lymphadenectomy and regard arterial infiltration as a contraindication for resection. However, the
rate of portal vein resection varied from 0% to 28%. No consensus is seen on the type of surgery for malignancy and chronic
pancreatitis. After resection for pancreatic cancer less than one fourth of the patients receive adjuvant therapy. The results
of our analysis in Germany confirm that pancreatic head resection can be performed with low mortality in specialized units.
Variations in indications, operative technique, and perioperative care may demonstrate the lack of evidence-based data and/or
personal and institutional experience. The low number of patients receiving adjuvant therapy after resection of pancreatic
cancer suggests that more efforts must be made to establish novel adjuvant therapies under randomized study conditions.
Presented at the Forty-Sixth Annual Meeting of The Society for Surgery of the Alimentary Tract, Chicago, Illinois, May 14–18,
2005 (oral presentation). 相似文献
102.
高龄骨折患者术后并发症的观察与护理 总被引:1,自引:0,他引:1
自2004年1月至2005年12月,对31例70岁以上的骨折患者施行了手术,通过精心治疗与护理,有效地预防了并发症的发生。现将观察与护理体会报告如下。1临床资料本组31例,其中男19例,女12例;年龄70~95岁,平均78岁。股骨颈骨折11例,股骨粗隆间骨折20例。行全髋关节置换6例,人工股骨头置换10例,动力髋15例,伤后3~18 d手术。手术入路采用髋外侧或后外侧入路,术后常规应用抗生素7~10 d,均不应用止血类药物。2术后并发症的观察与护理2·1切口感染术后1~3 d可有暂时性体温升高,如不超过38·5℃,可嘱其多饮水,无须特殊处理;如持续低热,要及时查明原因,对症… 相似文献
103.
降调节对卵子质量的影响 总被引:2,自引:0,他引:2
近10余年来,在体外受精一胚胎移植(IVF-ET)周期中应用促性腺激素释放激素激动剂(GnRH-a)进行控制性卵巢刺激(COS)已成为普遍采用的方法,其主要原因是GnRH-a可以促进卵巢内多个卵泡同步发育和成熟,抑制内源性黄体生成素(LH)峰,阻遏卵泡过早黄素化及卵子早熟。由于GnRH-a在IVF-ET进行降调节COS中的应用不同,可将COS方案分为长方案和短方案。[第一段] 相似文献
104.
105.
输卵管积水处理方式对体外受精-胚胎移植临床结局的影响 总被引:4,自引:0,他引:4
目的探讨输卵管积水的不同腹腔镜手术处理方式对体外受精-胚胎移植(IVF-ET)临床结局的影响。方法回顾性分析2006年1月至2007年7月因输卵管因素在本中心行常规IVF-ET治疗的294例不育患者的资料,按IVF-ET前腹腔镜下输卵管积水处理方式分组:A组:双侧输卵管近端结扎术28例;B组:双侧输卵管造口术42例;C组:双侧输卵管切除术64例;D组:输卵管阻塞不伴积水80例;E组:单或双侧输卵管积水80例。比较5组患者在IVF-ET周期中卵巢对超排卵的反应性及临床结局的影响。结果C组的窦卵泡数少于B组,发育的卵泡数及获卵数少于其他4组,均有显著性差异(P<0.05);与其他4组相比,C组使用促性腺激素(Gn)的支数最多,但无显著性差异(P>0.05);E组的胚胎植入率为15.9%,临床妊娠率为27.5%,为各组间最低,其中胚胎植入率与A、C和D组比较有显著性差异,临床妊娠率与A和D组比较有显著性差异(P<0.05);各组流产率E组最高(22.7%),其次为B组(14.4%),E与C组(4%)比较有显著性差异(P<0.05);异位妊娠率E组最高,其次为B组,但各组间无显著性差异(P>0.05)。结论输卵管积水对IVF-ET结局有负面影响,对输卵管积水进行适当预处理有助于改善其临床结局。输卵管近端结扎术不降低卵巢反应性,异位妊娠率及流产率低,是IVF-ET前输卵管积水预处理较理想手术方式。 相似文献
106.
W. E. Uber S. E. Self A. B. Van Bakel N. L. Pereira 《American journal of transplantation》2007,7(9):2064-2074
Acute antibody-mediated rejection (AMR) in heart transplantation is often associated with hemodynamic compromise, and is associated with increased mortality and development of accelerated transplant coronary artery disease (TCAD). The diagnosis of AMR has historically been controversial and outcomes with aggressive immunosuppressive therapy including plasmapheresis and cyclophosphamide are poor. Advances in diagnostic techniques like the demonstration of immunopathologic evidence for antibody-mediated rejection by deposition of the complement split product C4d in tissue and detection of anti-HLA antibodies by flow cytometry will assist in further characterizing AMR. Immunosuppression targeting B-lymphocytes and use of m-TOR inhibitors to alter the predilection to develop TCAD and improve survival in AMR remains to be proven. 相似文献
107.
腹腔镜下处理输卵管积水对体外受精胚胎移植结局的影响 总被引:3,自引:2,他引:1
目的探讨腹腔镜下处理输卵管积水对体外受精胚胎移植(in vitro fertilization and embryo transfer, IVF-ET)结局的影响.方法 2002~2005年在我院行IVF-ET伴输卵管积水的53例分3个研究组:①未处理组17例,仅行IVF-ET,未对积水进行处理;②直接切除组17例,行IVF-ET术前在腹腔镜下处理输卵管积水;③失败后切除组19例,IVF-ET失败后腹腔镜下处理输卵管积水后再行IVF-ET.结果未处理组新鲜移植周期妊娠率15.8%(3/19),解冻周期妊娠率10.5%(2/19),平均周期妊娠率13.2%(5/38),累积活胎率17.6%(3/17);直接切除组分别为36.8%(7/19),23.1%(3/13),30.3%(10/32),41.7%(8/17);失败后切除组分别为16.7%(2/12),58.3%(14/24),44.4%(16/36),73.7%(14/19).失败后切除组的解冻周期妊娠率、平均周期妊娠率及累积活胎率均高于未处理组(χ2=10.374,P=0.001;χ2=8.903,P=0.003;χ2=11.305,P=0.001),直接切除组平均周期妊娠率及累积活胎率呈高于未处理组的趋势(χ2=3.377,P=0.066;χ2=3.360,P=0.067).结论输卵管积水降低IVF-ET的妊娠率,妊娠结局不良,腹腔镜下处理输卵管积水后再行IVF-ET提高妊娠率,获得良好的妊娠结局. 相似文献
108.
109.
110.
Summary Human fibrin glue (Tissucol) is a plasma-derived compound endowed with adhesive and hemostatic properties and possessing a specific local anti-infection function mediated through activation of nonspecific immunity elements. The aim of this study is to show that in patients who have undergone prolonged reconstructive plastic surgery following cancer resection, Tissucol decreases infectious complications as compared to a control group. Between June 1985 and February 1988, 51 subjects were treated with fibrin glue during reconstruction operations. Analysis of the results showed that Tissucol produced a statistically significant reduction both of immediate complications, such as inflammation and partial separation of the surgical wound, and of delayed complications, such as scar hypertrophy and cutaneous fistulae. In conclusion, patients treated with Tissucol showed a better quality of surgical wound, a more rapid postoperative functional recovery and consequently a decrease in the duration of hospitalization. 相似文献